CJC-1295 with DAC (Drug Affinity Complex) is a long-acting growth hormone releasing hormone analogue. The DAC modification is a lysine residue linked to a reactive chemical group that enables covalent binding to serum albumin after administration, significantly extending the biological half-life compared to the non-DAC version.<\/p>\n
This extended duration is achieved through reversible albumin binding, creating a circulating reservoir that releases active peptide over an extended period. Research has shown that the DAC modification extends the half-life from approximately 30 minutes (non-DAC) to several days, fundamentally changing the pharmacokinetic profile.<\/p>\n
Studies have compared the pharmacodynamics of CJC-1295 DAC versus the non-DAC version, examining differences in GH release patterns. The DAC version produces more sustained GH elevation, while the non-DAC version produces pulsatile release more similar to natural physiological patterns.<\/p>\n
Research has investigated the implications of continuous versus pulsatile GH stimulation on downstream effects including IGF-1 levels, body composition changes, and receptor desensitisation. These studies help characterise the different research applications for each variant.<\/p>\n
Gen Ex Peptides supplies CJC-1295 DAC tested at an Australian university laboratory not generic overseas certificates. Each batch is verified for purity (99%) using HPLC and mass spectrometry.<\/p>\n","protected":false},"excerpt":{"rendered":"
CJC-1295 DAC 5mg, a long-acting GHRH analogue with extended half-life. (99%) Purity verified here on Australian soil at a major\u00a0Australian university in Melbourne.<\/strong><\/p>\n","protected":false},"featured_media":1469,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[33,31],"product_tag":[],"class_list":{"0":"post-1468","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-growth-hormone-secretagogues","7":"product_cat-shop-all-australian-aminos","9":"first","10":"instock","11":"shipping-taxable","12":"purchasable","13":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/genexpeptides.com.au\/index.php\/wp-json\/wp\/v2\/product\/1468","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/genexpeptides.com.au\/index.php\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/genexpeptides.com.au\/index.php\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/genexpeptides.com.au\/index.php\/wp-json\/wp\/v2\/comments?post=1468"}],"version-history":[{"count":1,"href":"https:\/\/genexpeptides.com.au\/index.php\/wp-json\/wp\/v2\/product\/1468\/revisions"}],"predecessor-version":[{"id":1470,"href":"https:\/\/genexpeptides.com.au\/index.php\/wp-json\/wp\/v2\/product\/1468\/revisions\/1470"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/genexpeptides.com.au\/index.php\/wp-json\/wp\/v2\/media\/1469"}],"wp:attachment":[{"href":"https:\/\/genexpeptides.com.au\/index.php\/wp-json\/wp\/v2\/media?parent=1468"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/genexpeptides.com.au\/index.php\/wp-json\/wp\/v2\/product_brand?post=1468"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/genexpeptides.com.au\/index.php\/wp-json\/wp\/v2\/product_cat?post=1468"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/genexpeptides.com.au\/index.php\/wp-json\/wp\/v2\/product_tag?post=1468"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}