Ipamorelin is a synthetic pentapeptide growth hormone secretagogue originally developed by Novo Nordisk (research code NNC 26-0161). It acts as a selective agonist at the growth hormone secretagogue receptor (GHS-R1a), which is the same receptor targeted by ghrelin, the endogenous hunger hormone.<\/p>\n
The peptide sequence (Aib-His-D-2-Nal-D-Phe-Lys-NH\u2082) includes several modified amino acids that contribute to its selectivity and stability. Research has characterised Ipamorelin as one of the most selective GHS-R1a agonists available, with minimal effects on cortisol, prolactin, and other hormones in preclinical studies.<\/p>\n
Studies have compared Ipamorelin\u2019s pharmacology with other growth hormone secretagogues including GHRP-6, GHRP-2, and hexarelin. Research indicates that Ipamorelin demonstrates dose-dependent GH release with a more favourable selectivity profile than earlier generation secretagogues.<\/p>\n
The peptide has been studied in various research contexts examining the GH\/IGF-1 axis, including investigations into pulsatile versus continuous GH release patterns. Research has also explored its potential interactions with GHRH analogues in combined administration protocols.<\/p>\n
Gen Ex Peptides supplies Ipamorelin tested at an Australian university laboratory not generic overseas certificates. Each batch is verified for purity (99%) using HPLC and mass spectrometry.<\/p>\n","protected":false},"excerpt":{"rendered":"
Ipamorelin 10mg, a selective growth hormone secretagogue for GH research. (99%) Purity verified here on Australian soil at a major\u00a0Australian university in Melbourne.<\/strong><\/p>\n","protected":false},"featured_media":1485,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[33,31],"product_tag":[],"class_list":{"0":"post-1484","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-growth-hormone-secretagogues","7":"product_cat-shop-all-australian-aminos","9":"first","10":"instock","11":"shipping-taxable","12":"purchasable","13":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/genexpeptides.com.au\/index.php\/wp-json\/wp\/v2\/product\/1484","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/genexpeptides.com.au\/index.php\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/genexpeptides.com.au\/index.php\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/genexpeptides.com.au\/index.php\/wp-json\/wp\/v2\/comments?post=1484"}],"version-history":[{"count":1,"href":"https:\/\/genexpeptides.com.au\/index.php\/wp-json\/wp\/v2\/product\/1484\/revisions"}],"predecessor-version":[{"id":1486,"href":"https:\/\/genexpeptides.com.au\/index.php\/wp-json\/wp\/v2\/product\/1484\/revisions\/1486"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/genexpeptides.com.au\/index.php\/wp-json\/wp\/v2\/media\/1485"}],"wp:attachment":[{"href":"https:\/\/genexpeptides.com.au\/index.php\/wp-json\/wp\/v2\/media?parent=1484"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/genexpeptides.com.au\/index.php\/wp-json\/wp\/v2\/product_brand?post=1484"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/genexpeptides.com.au\/index.php\/wp-json\/wp\/v2\/product_cat?post=1484"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/genexpeptides.com.au\/index.php\/wp-json\/wp\/v2\/product_tag?post=1484"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}