CJC-1295 NO DAC (10mg)

CJC-1295 No DAC 10mg (Mod GRF 1-29), a modified GHRH analogue for GH research. (99%) Purity verified here on Australian soil at The University of Melbourne.

CJC-1295 without DAC, also known as Mod GRF 1-29 or Modified GRF(1-29), is a synthetic analogue of growth hormone releasing hormone (GHRH). It consists of the first 29 amino acids of GHRH with four strategic amino acid substitutions designed to increase stability and resistance to enzymatic degradation.

The modifications at positions 2, 8, 15, and 27 (D-Ala², Gln⁸, Ala¹⁵, Leu²⁷) protect against degradation by dipeptidyl peptidase-IV (DPP-IV), extending biological activity compared to native GHRH while maintaining pulsatile release patterns that more closely mimic natural GH secretion.

Research has examined CJC-1295 No DAC’s effects on the GH/IGF-1 axis, comparing its pharmacokinetics and pharmacodynamics with native GHRH and other analogues. Studies have investigated its half-life, receptor binding affinity, and dose-response characteristics in preclinical models.

The peptide is often studied in combination with growth hormone secretagogues like Ipamorelin, as the two classes of compounds work through complementary mechanisms — GHRH analogues stimulate GH synthesis and release, while secretagogues amplify the release signal through the GHS-R1a receptor.

Gen Ex Peptides supplies CJC-1295 No DAC tested at an Australian university laboratory not generic overseas certificates. Each batch is verified for purity (99%) using HPLC and mass spectrometry.