TB-500 (10mg)

TB-500 10mg (Thymosin Beta-4 fragment) for tissue repair research. (99%) Purity verified here on Australian soil at The University of Melbourne.

TB-500 is a synthetic peptide representing the active region of Thymosin Beta-4 (Tβ4), a naturally occurring 43-amino acid protein found in high concentrations in platelets, wound fluid, and various tissues throughout the body. The peptide has been extensively studied in preclinical research since its initial characterisation.

The key feature of TB-500 is the LKKTETQ actin-binding motif, which is responsible for Thymosin Beta-4’s documented effects on cell migration and actin polymerisation. This sequence allows the peptide to interact with G-actin and regulate cytoskeletal dynamics in cellular models.

Research has examined TB-500’s role in regulating actin polymerisation, promoting cell migration, and modulating inflammatory responses in various tissue models. Studies have investigated its effects on endothelial cells, keratinocytes, and fibroblasts in wound healing research contexts.

The peptide has also been studied for its effects on angiogenesis and blood vessel formation. Research has explored TB-500’s interaction with signalling pathways involved in tissue remodelling, including its effects on matrix metalloproteinases and growth factor expression.

Gen Ex Peptides supplies TB-500 tested at an Australian university laboratory not generic overseas certificates. Each batch is verified for purity (99%) using HPLC and mass spectrometry.